In eukaryotes, activator proteins bind to _____; generalized transcription factors bind to _____7/10/2023 In prokaryotes, the two processes are closely coupled (Figure 28.15). The dissociation of Ï allows the core enzyme to proceed along the DNA template, synthesizing mRNA in the 5â² to 3â² direction at a rate of approximately 40 nucleotides per second. Much work is still going on to determine the structure and function of each of the parts of the preinitiation complex. In Eukaryotes, transcription factors, rather than the enzymes themselves, are principally responsible for recognizing the promoter. ![]() In eukaryotes, these two functions are The initiation of transcription in eukaryotes involves the binding of several transcription factors to complex promoter sequences that are usually located upstream of the gene being copied. ![]() Do you have PowerPoint slides to share? Two additional general transcription factors, IIE and IIH, are required for the unwinding of the linear DNA but are not considered part of the core enzyme.
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